Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease

Authors
Uitti, RJ Wharen, RE Turk, MF
Citation
Rj. Uitti et al., Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease, NEUROLOGY, 51(6), 1998, pp. 1755-1757
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
51
Issue
6
Year of publication
1998
Pages
1755 - 1757
Database
ISI
SICI code
0028-3878(199812)51:6<1755:EOLTOM>2.0.ZU;2-6
Abstract
We evaluated motor function in 41 consecutive PD patients undergoing unilat eral MRI/microelectrode-guided posteroventral pallidotomy to determine whet her the motor effects of levodopa therapy change after surgery. Total Unifi ed Parkinson's Disease Rating Scale motor "off" and motor "on" subscores al l improved and the rapidity of action, magnitude, and duration of motor res ponse to levodopa therapy were all maintained after pallidotomy.