Influence of computed tomography on pretherapeutic tumor staging in head and neck cancer patients

Refinements in radiographic techniques have resulted in increased use of ra diographic studies in the evaluation of patients with head and neck cancer over the past 20 years. To assess the impact of such studies, we compared t umor clinical stages based solely on physical-examination findings with tho se obtained with the addition of CT findings. This study was accomplished t hrough case review of 81 head and neck cancer patients who underwent CT aft er preliminary TNM-stage assignment as determined on the basis of physical examination alone. In this cohort, 44 patients (54%) had a change in assign ed clinical stage. We reviewed individual anatomic sites to determine where CT was found to be most useful in modifying tumor stage. Changes in tumor and nodal stage were found across all major sites of the head and neck. Tum ors of the hypopharynx were the most likely to change stage (90%) on the ba sis of CT findings, whereas tumors of the glottic larynx were least likely to undergo a change in stage (16%), The therapeutic implications of these f indings are discussed in the context of the published literature.