1H-Benzotriazol-1-yl methanesulfonate: A regioselective N-mesylating reagent

Authors
Kim, SY Sung, ND Choi, JK Kim, SS
Citation
Sy. Kim et al., 1H-Benzotriazol-1-yl methanesulfonate: A regioselective N-mesylating reagent, TETRAHEDR L, 40(1), 1999, pp. 117-120
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
1
Year of publication
1999
Pages
117 - 120
Database
ISI
SICI code
0040-4039(19990101)40:1<117:1MARNR>2.0.ZU;2-8
Abstract
1H-Benzotriazol-1-yl methanesulfonate has been found to be an effective rea gent in selective mesylation for differentiating amino groups from one anot her. In a molecule with both primary and secondary amino groups, mesylation only occurred at the primary amino group. When a compound contains both am ino and hydroxy groups, the reagent selectively mesylated at the amino grou ps. (C) 1998 Elsevier Science Ltd. All rights reserved.