Enantioselective synthesis of the 4-hydroxy buteneolide terminus of mucocin and related annonaceous acetogenins

Authors
Evans, PA Murthy, VS
Citation
Pa. Evans et Vs. Murthy, Enantioselective synthesis of the 4-hydroxy buteneolide terminus of mucocin and related annonaceous acetogenins, TETRAHEDR L, 39(52), 1998, pp. 9627-9628
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
39
Issue
52
Year of publication
1998
Pages
9627 - 9628
Database
ISI
SICI code
0040-4039(199812)39:52<9627:ESOT4B>2.0.ZU;2-A
Abstract
The 4-hydroxy buteneolide terminus 3, applicable to mucocin 1 and related a nnonaceous acetogenins, was prepared in an expeditious manner from the sele nocarbonate 2 via an intramolecular acyl radical cyclization followed by an enantioselective Lewis-acid catalyzed Keck-allylation reaction. (C) 1998 E lsevier Science Ltd. All rights reserved.