Regiospecific 4 '-O-beta-glucosidation of isoflavones

Authors
Lewis, PT Wahala, K
Citation
Pt. Lewis et K. Wahala, Regiospecific 4 '-O-beta-glucosidation of isoflavones, TETRAHEDR L, 39(51), 1998, pp. 9559-9562
Citations number
25
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
39
Issue
51
Year of publication
1998
Pages
9559 - 9562
Database
ISI
SICI code
0040-4039(199812)39:51<9559:R4'OI>2.0.ZU;2-X
Abstract
The first stereospecific synthesis of isoflavone-4'-O-beta-glucosides from unprotected isoflavone aglycones is presented. The procedure, involving a s olid/liquid crown ether catalysed phase transfer system has been used for t he synthesis of daidzein 4'-O-beta-glucoside 3, genistein 4'-O-beta-glucosi de 4, and of the isoflavone-7-O-beta-glucosides genistin and daidzin in imp roved yields. (C) 1998 Elsevier Science Ltd. All rights reserved.