An uncommon reaction to varicella vaccine has been urticaria. Based on two
reports of urticaria believed to be due to gelatin in recipients of measles
-mumps-rubella vaccine, we suspected gelatin as the cause of generalized ur
ticaria in two children after varicella vaccination. Intradermal testing wi
th gelatin yielded a wheal and flare reaction in both children. We conclude
that children known to be allergic to gelatin should not receive Oka/Merck
varicella Vaccine (VARIVAX(R)). (C) 1998 Elsevier Science Ltd. All rights
reserved.