A child with a t(11 ; 19)(q14-21;p12) in a pulmonary mucoepidermoid carcinoma

Citation
G. Stenman et al., A child with a t(11 ; 19)(q14-21;p12) in a pulmonary mucoepidermoid carcinoma, VIRCHOWS AR, 433(6), 1998, pp. 579-581
Citations number
13
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
ISSN journal
09456317 → ACNP
Volume
433
Issue
6
Year of publication
1998
Pages
579 - 581
Database
ISI
SICI code
0945-6317(199812)433:6<579:ACWAT;>2.0.ZU;2-K
Abstract
We report on a mucoepidermoid carcinoma (MEC) of the lung in a 6-year-old g irl with a t(11;19)(q14-21;p12) as the sole karyotypic abnormality. An appa rently identical t(11;19) has been reported previously in a MEC originating from the major and minor salivary glands. Our findings indicate that the t (11;19) is intimately associated with the mucoepidermoid phenotype and may be used as a diagnostic marker for this tumour type.