The science of crystals involves symmetry. Symmetry is also an excellent li
nk to other fields of human endeavor. The first scientific crystallographer
, Johannes Kepler, came to the idea of close packing when he was considerin
g the symmetry of snow crystals. When Louis Pasteur observed crystal and mo
lecular chirality, he opened a Pandora's box of the notion of the dissymmet
ry of the universe. Since the start of X-ray crystallography in 1912, empha
sis has been on single-crystal symmetry, and the held has moved from triump
h to triumph. In the late 1920s, however, interest in less than perfect str
uctures developed, leading to the establishment of molecular biology. Helic
al symmetries were found to characterize life's most important molecules. S
ymmetry considerations were decisive in these: discoveries, which stimulate
d the expansion of the symmetry concept. In the mid-1980s, the belief that
fivefold symmetry was a noncrystallographic symmetry crumbled, and the conc
ept of the crystal had to be revised. Crystallography has now become the sc
ience of structures. Symmetry has helped crystallography to influence the a
rts. This tends to unify our culture - a side effect of the enormous work o
f uncovering the secrets of matter for the betterment of human life.