IODINE-ZINC EXCHANGE-REACTIONS MEDIATED BY I-PR2ZN, A NEW PREPARATIONOF SECONDARY ZINC REAGENTS

Authors
MICOUIN L KNOCHEL P
Citation
L. Micouin et P. Knochel, IODINE-ZINC EXCHANGE-REACTIONS MEDIATED BY I-PR2ZN, A NEW PREPARATIONOF SECONDARY ZINC REAGENTS, Synlett, (3), 1997, pp. 327
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
3
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):3<327:IEMBIA>2.0.ZU;2-C
Abstract
By treatment with i-Pr2Zn, functionalized secondary alkyl iodides unde rgo a smooth iodine-zinc exchange reaction leading to polyfunctional s econdary dialkylzinc derivatives. Remarkably, i-Pr2Zn generated in sit u from i-PrMgBr and ZnBr2 undergoes this exchange reaction almost 200 times faster than salt free i-Pr2Zn and constitutes a practical source of i-Pr2Zn for the performance of exchange reactions.