CANAVANINE DERIVATIVES USEFUL IN PEPTIDE-SYNTHESIS

The objective of this work is to investigate the possibilities for int roducing the currently used N alpha-, N-G- and C-protective groups int o the canavanine molecule and the preparation of canavanines selective ly blocked at the guanidino function. These novel compounds will find application in the synthesis of canavanine derivatives expected to be amino acid antimetabolites and of canavanine modified biologically act ive peptides.