The standard coronary stent implantation technique requires routine predila
tation of the target lesion with a balloon catheter. In this study, we pros
pectively studied the feasibility and efficiency of elective coronary stent
implantation without predilatation. In 94 patients who presented with vari
ous ischemic syndromes, direct implantation of 100 balloon expandable ACS M
ultiLink stents (7 over-the-wire, 93 rapid exchange) was attempted in 100 c
oronary lesions selected to have favorable characteristics. The stent cross
ed the lesion without predilatation in 97 cases (97%) and was successfully
deployed in 93 (95.8%). in 4 patients, adjunctive high-pressure postdilatat
ion was necessary to achieve optimal stent expansion. Reference vessel diam
eter was 3.12 +/- 0.77 mm and lesion length 8.8 +/- 2.7 mm. Minimal luminal
diameter increased from 0.95 +/- 0.38 mm to 2.98 +/- 0.28 mm and diameter
stenosis decreased from 71 +/- 11% to 8 +/- 11% after stenting. One occlusi
ve dissection was treated by a second stent. There were no major in-hospita
l complications. At 1 month follow-vp, 1 subacute thrombotic occlusion occu
rred. These results indicate that in a carefully selected coronary lesion s
ubset, elective stent implantation without predilatation can be safely and
effectively performed. The long-term results of this approach and possible
advantages over the conventional implantation techniques remain unclear and
need to be evaluated in further clinical studies. (C) 1998 by Excerpta Med
ico, Inc.