We report a case of toxic multinodular goiter with severe symptomatic hyper
thyroidism in a female diagnosed 5 months after successful renal transplant
ation. To our knowledge, this is the first well-documented case of hyperthy
roidism in a renal transplant recipient that responded well, to methimazole
. Special attention should be made to the use of methimazole and the possib
le interaction with immunosuppressive drugs.