Acute infectious disease presentations among many at-risk patient groups (e
g, uninsured, homeless, and recent immigrants) are frequently seen in emerg
ency departments. Therefore EDs may be useful sentinel sites for infectious
disease surveillance. This article describes the background, development,
and implementation of EMERGEncy ID NET, an interdisciplinary, multicenter,
ED-based network for research of emerging infectious diseases. EMERGEncy ID
NET was established in cooperation with the National Center for Infectious
Diseases, Centers for Disease Control and Prevention (CDC) as part of the
CDC's strategy to expand and complement existing disease detection and cont
rol activities. The network is based at 11 university-affiliated, urban hos
pital EDs with a combined annual patient visit census of more than 900,000.
Data are collected during ED evaluation of patients with specific clinical
syndromes, and are electronically stored, transferred, and analyzed at a c
entral receiving site. Current projects include investigation of bloody dia
rrhea and the prevalence of Shiga toxin-producing Escherichia cell, animal
exposures and rabies postexposure prophylaxis practices, seizures and preva
lence of neurocysticercosis, nosocomial ED Mycobacterium tuberculosis trans
mission, and hospital isolation bed use for adults admitted for pneumonia o
r suspected tuberculosis. EMERGEncy ID NET also was developed to be a mecha
nism for rapidly responding to new diseases or epidemics. Future plans incl
ude study of antimicrobial use, meningitis, and encephalitis, and considera
tion of other public health concerns such as injury and national and intern
ational network expansion.