Resolution of (+/-)-trans-2-phenylcyclohexan-1-ol by lipases from Candida rugosa: effect of catalyst source and reaction conditions

Authors
del Rio, JL Faus, I
Citation
Jl. Del Rio et I. Faus, Resolution of (+/-)-trans-2-phenylcyclohexan-1-ol by lipases from Candida rugosa: effect of catalyst source and reaction conditions, BIOTECH LET, 20(11), 1998, pp. 1021-1025
Citations number
12
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
BIOTECHNOLOGY LETTERS
ISSN journal
01415492 → ACNP
Volume
20
Issue
11
Year of publication
1998
Pages
1021 - 1025
Database
ISI
SICI code
0141-5492(199811)20:11<1021:RO(BLF>2.0.ZU;2-J
Abstract
Candida rugosa lipase resolved trans-2-phenylcyclohexan-1-ol. A commercial and a laboratory preparation were compared and better results were obtained with the latter (E >200). Both enzyme preparations were strongly dependent on the substrate concentration for their enantioselectivity. This effect c ould be due to the presence of an esterase activity unspecific for trans-2- phenylcyclohexan-1-ol.