Oral and systemic effects of prolonged minocycline therapy

The following case report shows the unfortunate side effects of minocycline therapy used in the management of facial acne. All three features of disco loration affecting the skin, bone and dentition were found. A 46-year-old p atient presented with adult onset discoloration of the dentition following prolonged minocycline therapy. In addition, oral and cutaneous pigmentation were noted. Unfortunately, the undesirable cosmetic appearance of facial a cne was exchanged for permanent discoloration of the dentition. When consid ering prolonged minocycline therapy, patients would benefit from dialogue b etween the medical and dental practitioners, so that the risk of this poten tial side effect can be assessed in a more informed way.