Citation
Mi. Atta-ur-rahman,"choudhary et al., New withanolides from Withania coagulans, CHEM PHARM, 46(12), 1998, pp. 1853-1856
Citations number
20
Categorie Soggetti
Chemistry & Analysis
Journal title
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN journal
00092363
→ ACNP
Volume
46
Issue
12
Year of publication
1998
Pages
1853 - 1856
Database
ISI
SICI code
0009-2363(199812)46:12<1853:NWFWC>2.0.ZU;2-T
Abstract
Three new withanolides, coagulins M, N, and O were isolated from the whole
plant of Withania coagulans. Their structures were established as (14R,17R,
20 xi,22R)-5 alpha,6 beta,27-trihydroxy-14,20-epoxy-1-oxo-witha-24-enolide
(1), (14R,17S,20 xi,22R)-15 alpha,17-dihydroxy-14,20-epoxy-3 beta-(O-beta-D
-glucopyranosyl)-1-oxo-witha-5,24-dienolide (2) and (14R,20 xi,22R)-14,20-d
ihydroxy-3 beta(O-beta-D-glucopyranosyl)-1-oxo-witha-5,24-dienolide (3) res
pectively, by extensive spectroscopic studies.