ASSOCIATION OF EXTRACRANIAL CAROTID ARTERIAL-DISEASE, PRIOR ATHEROTHROMBOTIC BRAIN INFARCTION, SYSTEMIC HYPERTENSION, AND LEFT-VENTRICULAR HYPERTROPHY WITH THE INCIDENCE OF NEW ATHEROTHROMBOTIC BRAIN INFARCTION AT 45-MONTH FOLLOW-UP IN 1,482 OLDER PATIENTS
Ws. Aronow et al., ASSOCIATION OF EXTRACRANIAL CAROTID ARTERIAL-DISEASE, PRIOR ATHEROTHROMBOTIC BRAIN INFARCTION, SYSTEMIC HYPERTENSION, AND LEFT-VENTRICULAR HYPERTROPHY WITH THE INCIDENCE OF NEW ATHEROTHROMBOTIC BRAIN INFARCTION AT 45-MONTH FOLLOW-UP IN 1,482 OLDER PATIENTS, The American journal of cardiology, 79(7), 1997, pp. 991
Comparison of 239 older patients with 40% to 100% extracranial carotid
arterial disease (ECAD) with 1,243 older patients with no significant
ECAD showed a higher prevalence of systemic hypertension, left ventri
cular (LV) hypertrophy, and prior atherothrombotic brain infarction (A
BI) and a higher incidence of new ABI in patients with ECAD than in pa
tients without ECAD. A multivariate Cox regression model showed that i
ndependent predictors of new ABI were ECAD (risk ratio = 2.5), systemi
c hypertension (risk ratio = 2.3), prior ABI (risk ratio = 2.3), LV hy
pertrophy (risk ratio = 2.3), and male sex (risk ratio = 1.3).