The structure, catalytic mechanism and regulation of adenylyl cyclase

Authors
Tesmer, JJG Sprang, SR
Citation
Jjg. Tesmer et Sr. Sprang, The structure, catalytic mechanism and regulation of adenylyl cyclase, CURR OP STR, 8(6), 1998, pp. 713-719
Citations number
46
Categorie Soggetti
Biochemistry & Biophysics
Journal title
CURRENT OPINION IN STRUCTURAL BIOLOGY
ISSN journal
0959440X → ACNP
Volume
8
Issue
6
Year of publication
1998
Pages
713 - 719
Database
ISI
SICI code
0959-440X(199812)8:6<713:TSCMAR>2.0.ZU;2-2
Abstract
The recent structure determinations of the mammalian effector enzyme adenyl yl cyclase reveal the structure of its catalytic core, provide new insights into its catalytic mechanism and suggest how diverse signaling molecules r egulate its activity.