Association of endometrial carcinoma with the malignant tumors in families

The clinical-genealogic analysis of 262 patients with endometrial carcinoma at the Belaya Tserkov interdistrict dispensary was conducted. The informat ion about the morbidity of 1777 relatives of the first relationship's degre e and 2647 relatives of the second relationship's degree were received. Can cer was detected in 41.22% pedigrees, endometrial carcinoma, cancer of the woman reproduction system and cancer of gastrointestinal tract were detecte d more often than other tumors. Synchronous and metachronous primary multip le tumors were detected in 19 cases. Apparently it should be supposed that total predisposition to the development of the malignant neoplasms take pla ce both for probands and for their relatives. The results of investigation bear witness to the necessity of inspection of close relatives for the purp ose to reveal earlier forms of the malignant tumors in families with cancer .