Biochemical changes in serum due to Newcastle disease virus strains

The biochemical changes in serum of chickens following infection with 3 New castle disease virus (NDV) strains of varying virulence were studied in 6-w eek-old chickens. A marked decrease in total serum protein, serum albumin, cholesterol and alkaline phosphatase (ALP) with increase of uric acid and s erum glutamate oxaloacetate transaminase (SGOT) were observed in chickens i nfected with velogenic strain of NDV. Infection with mesogenic strain incre ased SGOT and decreased ALP level in serum. Levels of cholesterol and uric acid increased in birds infected with lentogenic strain. Serum. glutamate p yruvate transaminase (SGPT) level did not change in the birds infected with any of the strains.