The differentiation of cardiac patients and healthy subjects according to the features of their circulation response to a mild neuropsychologic stressor

In cardiac patients the use of the same drugs with different homeostasis ty pes suggests the possibility of different results. This study was conducted to find the allocation of cardiac patients among groups according to the f eatures of their circulation response on a mild neuropsychologic stressor. Different groups had distinctly significant correlations and/or levels or c hanges of cortisol, testosterone? T-active lymphocytes, beta-lipoproteins, fibrinase, prothrombin index, fibrinolytic activity, immunoglobulins, and s o forth. A new, orginal method had been developed for this research. Differ ent types of circulation response on a mild neuropsychologic stressor had b een found in adult human males, both in healthy subjects and in cardiac pat ients, surviving acute myocardial infarction. These types appeared to have their background in neurohumoral homeostasis and molecular features. The de monstrated differences in neurohumoral homeostasis depended more heavily on the types of response discovered than on the presence or the absence of at herosclerosis. Differences in working behavior were found among patients in the three groups. The patients with the second type of hemodynamics had th e results of Platonov's table application greater at 20% than in other grou ps (p < 0.05). No significant difference was found between this group and h ealthy subjects in this parameter. The variance coefficient of simple react ion time in the first group of patients was less at the same 20% than in th e second and third groups (p < 0.05). The value of the variance coefficient in the first group of patients was the same as in healthy subjects. The pr oposed differentiation method, based on tetrapolar impedance reoplethysmogr aphy, does net require the onset of heart failure symptoms to be present du ring testing. It does not check the exertional tolerance of a patient and m ay not lead to congestive heart failure. The interpretation of results does not rely heavily on experts? choice and does not require echocardiography, allowing easy automation and usability during various mild stressor applic ations at any workplace. The method can be applied to both cardiac patients and healthy subjects.