We report the case of a Spanish 60-year-old female who presented in 1997 wi
th onychomycosis of the left thumbnail following an injury caused by a fres
h fish bone. Microsporum racemosum was repeatedly cultured from nail scrapi
ngs, and its identity was confirmed by sequencing the isolate's ITS1/ITS2 a
nd 5.8S rRNA regions. The patient was successfully treated with itraconazol
e, which was administered for 12 weeks. This represents the first case of o
nychomycosis due to M. racemosum and the first time that this species has b
een isolated from a human in Europe.