Early diagnosis of ALS/MND

With the advent of a specific biological therapy for ALS there is an increa sing imperative for early diagnosis. As new, more effective therapies becom e available, this will become more important. It is intuitively probable th at early therapy will prevent disability in this otherwise relentlessly pro gressive disorder. The difficulties posed by this need for early diagnosis in clinical practice are discussed. (C) 1998 Published by Elsevier Science B.V. All rights reserved.