Language impairment in motor neurone disease

Evidence from recent neuropsychological studies of patients with motor neur one disease (MND) has demonstrated that some patients have cognitive impair ment. This challenges traditional teaching that MND is a disease with only motor symptoms. Language processing in MND patients has so far not been stu died in any depth, but has only been touched upon as a part of general cogn ition. This study has assessed nine MND subjects on a range of standardised language assessments and compared their performance to that of nine contro l subjects. Although this is a small experimental sample of subjects, the r esults of this study indicate that language impairment is present in some p atients with MND. The deficits are subtle and only exposed on formal testin g. It is not possible to define the nature of the language impairment from this restricted set of data, but there was evidence of some deficits in a s ub-group of MND patients on tasks involving naming, auditory comprehension of complex sentences, some semantic tests and spelling. The implications of these findings are discussed in relationship to the clinical management of patients with MND. (C) 1998 Elsevier Science B.V. All rights reserved.