A 25-year-old woman with anomalous circulation to the right leg was seen wi
th a symptomatic aneurysm of the abnormal vessel. The artery, which did sha
re some features of the classic persistent sciatic artery, also had importa
nt differences that were not previously described in the Literature. The pa
tient manifested several associated vascular and nonvascular congenital ano
malies. She underwent resection of the aneurysm and primary operative repai
r of the artery without difficulty. An embryologic interpretation is offere
d, and the clinical implications and management strategy are discussed.