St John's wort (SJW) was introduced into Australia during the 1880s for med
icinal purposes, but was subsequently declared a noxious weed. There is now
a resurgence of interest in the therapeutic properties of this herb. In pa
rticular use of SJW as an antidepressant has increased in recent months owi
ng to reports of its effectiveness and safety. Nevertheless, the controlled
trials available have limitations, increasing use of SJW in the community
poses a variety of questions. For example, should medical practitioners bec
ome more knowledgeable about the effects and interactions of alternative re
medies? What are the ethical and medical implications of "antidepressant" p
rescribing by non-medical per,sons? Who is to fund further research and tre
atment studies? How can quality of SJW preparations be guaranteed?