Mitochondrial gene order is not conserved in arthropods: Prostriate and metastriate tick mitochondrial genomes

Citation
Wc. Black et Rl. Roehrdanz, Mitochondrial gene order is not conserved in arthropods: Prostriate and metastriate tick mitochondrial genomes, MOL BIOL EV, 15(12), 1998, pp. 1772-1785
Citations number
63
Categorie Soggetti
Biology,"Experimental Biology
Journal title
MOLECULAR BIOLOGY AND EVOLUTION
ISSN journal
07374038 → ACNP
Volume
15
Issue
12
Year of publication
1998
Pages
1772 - 1785
Database
ISI
SICI code
0737-4038(199812)15:12<1772:MGOINC>2.0.ZU;2-#
Abstract
The entire mitochondrial genome was sequenced in a prostriate tick, Ixodes hexagonus, and a metastriate tick, Rhipicephalus sanguineus. Both genomes e ncode 22 tRNAs, 13 proteins, and two ribosomal RNAs. Prostriate ticks are b asal members of Ixodidae and have the same gene order as Limulus polyphemus . In contrast, in R. sanguineus a block of genes encoding NADH dehydrogenas e subunit 1 (ND1), tRNA(Leu (UUR)), tRNA(Lett (CUN)), 16S rDNA, tRNA(Val), 12S rDNA, the control region, and the tRNA(Ile) and tRNA(Glm) have transloc ated to a position between the tRNA(Glu) and tRNA(Phe) genes. The tRNA(Cys) gene has translocated between the control region and the tRNA(Met) gene, a nd the tRNA(Leu(CUN)) gene has translocated between the tRNA(Ser (UCN)) gen e and the control region. Furthermore, the control region is duplicated, an d both copies undergo concerted evolution. Primers that flank these rearran gements confirm that this gene order is conserved in all metastriate ticks examined. Correspondence analysis of amino acid and codon use in the two ti cks and in nine other arthropod mitochondrial genomes indicate a strong bia s in R. sanguineus towards amino acids encoded by AT-rich codons.