PRESERVING A GLOBULAR PROTEIN SHAPE ON GLASS SLIDES - A SELF-ASSEMBLED MONOLAYER APPROACH

Authors
YANG ZH YU H
Citation
Zh. Yang et H. Yu, PRESERVING A GLOBULAR PROTEIN SHAPE ON GLASS SLIDES - A SELF-ASSEMBLED MONOLAYER APPROACH, Advanced materials, 9(5), 1997, pp. 426
Citations number
25
Categorie Soggetti
Material Science
Journal title
Advanced materials → ACNP
ISSN journal
09359648
Volume
9
Issue
5
Year of publication
1997
Database
ISI
SICI code
0935-9648(1997)9:5<426:PAGPSO>2.0.ZU;2-0
Abstract
The manufacture of low-cost, protein-friendly, biocompatible materials is important for biomedical applications. A method is presented for m aking glass surfaces-on which the globular protein shape is often lost -benign to proteins by covalently grafting relatively short poly(ethyl ene glycol) chains (functionalized with trimethylsilane, see Figure), which form a brush-like self-assembled monolayer.