Stage II vaginal cancer responding to chemotherapy with irinotecan and cisplatin: A case report

Authors
Umesaki, N Kawamura, N Tsujimura, A Ichimura, T Tanaka, T Ogita, S
Citation
N. Umesaki et al., Stage II vaginal cancer responding to chemotherapy with irinotecan and cisplatin: A case report, ONCOL REP, 6(1), 1999, pp. 123-125
Citations number
5
Categorie Soggetti
Oncology
Journal title
ONCOLOGY REPORTS
ISSN journal
1021335X → ACNP
Volume
6
Issue
1
Year of publication
1999
Pages
123 - 125
Database
ISI
SICI code
1021-335X(199901/02)6:1<123:SIVCRT>2.0.ZU;2-N
Abstract
We report a patient with stage II primary vaginal cancer whose tumor disapp eared on magnetic resonance imaging after a single course of neoajuvant che motherapy using irinotecan and cisplatin. The regimen was 60 mg/m(2) of cis platin (day 1) and 60 mg/m(2) of irinotecan (days 1, 8, 15). After addition of 1 course of cisplatin alone, radical surgery was performed. Histologica l examination of the excised tissue revealed no cancer cells. This is the f irst report on the good efficacy of chemotherapy with irinotecan and cispla tin for advanced vaginal cancer.