Congenital lower lip pits (Van der Woude syndrome): Presentation of 10 cases

Congenital lower lip pits are a rare developmental malformation of the lowe r lip, Clinically they present as bilateral depressions in the vermilion zo ne of the lower lip, It is important to be aware of this disorder because l ower lip pits have also been reported in a variety of other congenital diso rders and are associated with other malformations, Ten cases of this entity are presented, Nine of the 10 patients are members of two related families , The clinical and pathologic picture as well as some of the genetic and th erapeutic aspects of this peculiar condition are discussed.