Liver and spleen MRI findings in virus-associated hemophagocytic syndrome in a patient with acute lymphocytic leukemia

Virus-associated hemophagocytic syndrome is characterized by the phagocytos is of erthythrocytes and other blood elements in multiple organ systems, es pecially the liver and spleen. Magnetic resonance imaging (MRI) can suggest this diagnosis in the proper clinical setting by demonstrating multiple, r ounded signal voids in the spleen corresponding to hemosiderin deposition. We report a patient with virus-associated hemophagocytic syndrome during th e course of acute lymphocytic leukemia and MRI findings that suggested the preoperative diagnosis.