Total gastrointestinal endoscopy in the management of Peutz-Jeghers syndrome

Peutz-Jeghers syndrome was diagnosed in a 51-year-old woman presenting with iron deficiency anaemia. Upper gastrointestinal endoscopy and colonoscopy revealed several hamartomatous polyps in the stomach, duodenum and colon, w hich were removed. At a combined surgical-endoscopic procedure, 42 hamartom atous polyps were removed from the small intestine by snare polypectomy. Th is enteroscopic procedure reduces symptoms, may protect against future inte stinal obstructive episodes and their associated surgery, and may reduce th e risk of developing gastrointestinal malignancy.