Neuroimaging abnormalities in Indian patients with uncontrolled partial seizures

In this series we performed clinical and imaging evaluation of 77 consecuti ve patients with uncontrolled partial seizures. Single cerebral parenchymal calcification (22 patients) was the most common imaging abnormality. Nine patients had multiple punctate calcifications. Other CT abnormalities inclu ded persistence of granulomatous lesion (enhancing) or multiple cystic lesi ons. In nine patients (of 22 patients with a normal CT scan) magnetic reson ance imaging (MRI) was done, and two patients were seen to have circumscrib ed cystic lesions in the temporal lobes. The causes for uncontrolled seizur es in India are totally different and revolve around neurocysticercosis, as the parasite sometimes runs a very long course of evolution in the brain. Sequelae of neurocysticercosis in the form of calcification is often a focu s of epileptogenicity.