S. Ueno et al., Postoperative management following massive hepatectomy in a patient with Dubin-Johnson syndrome: Report of a case, SURG TODAY, 28(12), 1998, pp. 1274-1278
We report herein the ease of a 46-year-old man with Dubin-Johnson syndrome
(DJS) who was referred to our hospital to undergo a right hepatic lobectomy
for hepatocellular carcinoma. His complicated postoperative conjugated hyp
erbilirubinemia was successfully treated by hemopurification based on the i
ncreased level of serum hepatocyte growth factor (HGF). It is considered th
at hemopurification based on the early postoperative HGF levels has benefic
ial effects for patients with DJS; however, the specific role of hemopurifi
cation in the conjugated hyperbilirubinemia that develops postoperatively i
n these patients has not been determined.