Development of primary leiomyosarcoma of the sternum postirradiation: Report of a case

We report herein the case of a 30-year-oId man who developed a primary leio myosarcoma (LMS) 11 years after undergoing a median sternotomy for mediasti nal seminoma followed by 50 Gy radiotherapy. He was given two courses of ch emotherapy, resulting in 90% tumor regression, after which resection of the tumor with adjacent chest wall structures was carried out. Reconstruction was performed using a methylmethacrylate prosthesis prepared preoperatively . Postoperatively, he received two additional courses of chemotherapy and h as had no sign of recurrence for 45 months.