New enantiomerically pure 1,4-diols and 1,4-aminoalcohols have efficiently
been prepared in one and two steps, respectively, from a commercially avail
able camphor derived era fused lactone. Using sterically hindered amines, a
n aldol addition of two lactone molecules was observed and the stereochemis
try of the products was determined by X-ray crystallography. (C) 1998 Elsev
ier Science Ltd. All rights reserved.