New camphor derived chiral ligands for asymmetric synthesis

Citation
M. Knollmuller et al., New camphor derived chiral ligands for asymmetric synthesis, TETRAHEDR-A, 9(22), 1998, pp. 4009-4020
Citations number
21
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
9
Issue
22
Year of publication
1998
Pages
4009 - 4020
Database
ISI
SICI code
0957-4166(19981127)9:22<4009:NCDCLF>2.0.ZU;2-N
Abstract
New enantiomerically pure 1,4-diols and 1,4-aminoalcohols have efficiently been prepared in one and two steps, respectively, from a commercially avail able camphor derived era fused lactone. Using sterically hindered amines, a n aldol addition of two lactone molecules was observed and the stereochemis try of the products was determined by X-ray crystallography. (C) 1998 Elsev ier Science Ltd. All rights reserved.