Prospective investigation of metal allergy caused by metallic implants

Introduction: Allergies caused by metallic implants are often thought to be a reason for postoperative complications like bone necrosis or loosening o f the prosthesis. Patients and methods: In a prospective study, we investig ated allergic sensitivity against components of stainless steel implants, i ncluding titanium, in 112 patients shortly before surgical operation. The s ame tests were then repeated in 100 of these patients exactly one year afte r operation. There were three different kinds of procedures: 1. titanium im plants, mainly total hip replacements, 2. regular steel implants, 3. surger y without any implants (control group). Any differences from the process of regular healing were regarded as postoperative complications.