We describe an unusual case of cytomegalovirus (CMV) proctitis in an elderl
y adult with uncontrolled diabetes mellitus, who had not received immunosup
pressive therapy. Barium study and computed tomography showed large ulcerat
ion and sinus tract involving the rectum. CMV colitis is thought to occur a
lmost exclusively in immunosuppressed persons. In a nonimmunosuppressed hos
t, the infection is rarely reported.