The effectiveness of fluoxetine compared to placebo in the treatment of pos
t-stroke emotionalism was investigated in 20 patients using a double-blind
protocol. A total of 19 patients completed the study, as one subject in the
treatment group had to be withdrawn. The subjects receiving fluoxetine sho
wed a statistically and clinically significant improvement in their emotion
alism compared to the placebo group, which was apparent in the majority of
subjects from the third day of treatment.