A 50-year-old female presented with severe Coombs-positive haemolytic
anaemia. Chest roentgenogram revealed a right-sided paracardial mass i
n the anterior mediastinum that was proven to be a thymoma. The patien
t was treated with oral prednisone (1 mg/kg/day) and subsequent thymec
tomy. Haemolysis did not return although the direct Coombs test remain
ed weakly positive. In reviewing the literature 15 additional cases of
thymoma-associated autoimmune haemolytic anaemia were identified.