Lipase-catalyzed alcoholysis of 2-thioacetoxyethyl acetate

Authors
Iglesias, LE Baldessari, A
Citation
Le. Iglesias et A. Baldessari, Lipase-catalyzed alcoholysis of 2-thioacetoxyethyl acetate, AN AS QUIM, 86(3-6), 1998, pp. 203-207
Citations number
16
Categorie Soggetti
Chemistry
Journal title
ANALES DE LA ASOCIACION QUIMICA ARGENTINA
ISSN journal
03650375 → ACNP
Volume
86
Issue
3-6
Year of publication
1998
Pages
203 - 207
Database
ISI
SICI code
0365-0375(199805/12)86:3-6<203:LAO2A>2.0.ZU;2-B
Abstract
Lipase-catalyzed alcoholysis of 2-thioacetoxyethyl acetate is described. Re sults depended on the biocatalyst, the nucleophile and the substrate/nucleo phile ratio. When the reaction of the diester was carried out with one equi valent of 1-octanol under Candida antarctica lipase catalysis, it was found that 2-mercaptoethyl acetate is mainly obtained through S-acetyl removal.