Genotoxicity of Cr(VI) can be markedly lowered by complexation of the chromate anion

Authors
Gasiorowski, K Szyba, K Wozniak, D Cieslak-Golonka, M Rzepka-Materny, M
Citation
K. Gasiorowski et al., Genotoxicity of Cr(VI) can be markedly lowered by complexation of the chromate anion, BIOMETALS, 11(3), 1998, pp. 175-181
Citations number
33
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOMETALS
ISSN journal
09660844 → ACNP
Volume
11
Issue
3
Year of publication
1998
Pages
175 - 181
Database
ISI
SICI code
0966-0844(199809)11:3<175:GOCCBM>2.0.ZU;2-P
Abstract
We compared mutagenic activity of Cu(II) chromate complexes with 2,2'-bipyr idyl, 1,10-phenanthroline, and 2-(2'pyridyl)imidazole in the standard bacte rial tests. It was noticed that Cu(II) chromate complexes with 2-(2'pyridyl )imidazole exhibited the lowest mutagenic activity among ten tested complex es. We regard these results as promising for further syntheses of Cr(VI) - organic ligand complexes in the aspects of chromium mutagenicity quenching.