Lymphocytic autoimmune hidradenitis, cutaneous leucocytoclastic vasculitisand primary Sjogren's syndrome

We describe a 60-year-old woman with primary Sjogren's syndrome, mixed cryo globulinaemia and cutaneous leucocytoclastic vasculitis who developed gener alized hypohidrosis with a markedly decreased sweating response to pilocarp ine chloride. Skin biopsies demonstrated dense peri-eccrine lymphocytic inf iltrates in the lower reticular dermis, with glandular atrophy, From previo us studies it is evident that although patients with Sjogren's syndrome com monly have skin dryness, a lymphocytic hidradenitis has been documented onl y in a few cases. The histological findings in this case support the role o f autoimmune hidradenitis in the development of hypohidrosis in Sjogren's s yndrome.