We have reviewed the outcome of patients who have undergone thalamotomy for
the intention tremor of multiple sclerosis (MS). Twenty-four patients unde
rwent 29 procedures between 1988 and 1995. These patients were assessed for
the degree of disability due to MS and for the impairment of arm function
due to the tremor. Preoperative, postoperative and last follow-up score (me
an 2.2 years) were determined for arm function following thalamotomy. Patie
nt satisfaction, where expressed, was recorded. Twenty-three procedures (79
%) resulted in immediate improvement in arm function. Thirteen complication
s were recorded. Postoperative fatigue was demonstrated after seven procedu
res. Sustained benefit was seen after 18 procedures (62%). Out of 23 patien
ts whose opinions are recorded four were enthusiastic and 10 satisfied with
the outcome. We conclude that, despite severe disability, a majority of pa
tients with intention tremor of MS may still benefit from thalamotomy and a
re satisfied with the results.