Involvement of MLL gene in a t(10;11)(q22;q23) and a t(8;11)(q24;q23) identified by fluorescence in situ hybridization

Authors
Aventin, A La Starza, R Martinez, C Wlodarska, I Boogaerts, M Van den Berghe, H Mecucci, C
Citation
A. Aventin et al., Involvement of MLL gene in a t(10;11)(q22;q23) and a t(8;11)(q24;q23) identified by fluorescence in situ hybridization, CANC GENET, 108(1), 1999, pp. 48-52
Citations number
17
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
CANCER GENETICS AND CYTOGENETICS
ISSN journal
01654608 → ACNP
Volume
108
Issue
1
Year of publication
1999
Pages
48 - 52
Database
ISI
SICI code
0165-4608(19990101)108:1<48:IOMGIA>2.0.ZU;2-G
Abstract
We describe two cases of acute myeloblastic leukemia, classified as M4 and M5 in the French-American-British nomenclature, with an 11q23 rearrangement at karyotypic analysis. The involvement of the MLL gene with two new partn er loci on chromosome 10q22 and 8q24, respectively, was demonstrated by flu orescence in situ hybridization using a YAC clone B22B2L. (C) Elsevier Scie nce Inc., 1998.