Simple and convenient method for the synthesis of Delta(9(11))-3-hydroxy, Delta(1,4)- and Delta(1,4,9(11))-3-ketosteroids by selective dehydrogenation of 3-hydroxy-12-ketosteroids

Authors
Kongkathip, B Kongkathip, N Khunnavutimanotum, P Sakee, U
Citation
B. Kongkathip et al., Simple and convenient method for the synthesis of Delta(9(11))-3-hydroxy, Delta(1,4)- and Delta(1,4,9(11))-3-ketosteroids by selective dehydrogenation of 3-hydroxy-12-ketosteroids, CHEM LETT, (12), 1998, pp. 1207-1208
Citations number
28
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022 → ACNP
Issue
12
Year of publication
1998
Pages
1207 - 1208
Database
ISI
SICI code
0366-7022(199812):12<1207:SACMFT>2.0.ZU;2-9
Abstract
Hecogenin can be selectively dehydrogenated to the corresponding Delta(9(11 ))-3-hydroxysteroid, Delta(1,4)- and Delta(1,4,9(11))-3-ketosteroids by the treatment of 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) with a variety of solvents.