Seasonal allergic rhinitis causes considerable impairment of health-related
quality of life (HQRL). Generic quality-of-life questionnaires enable a co
mparison to be made between patients with different illnesses, but they oft
en have insufficient depth to measure specific problems that are important
to an individual with a particular condition. In order to overcome these sh
ortcomings, the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) wa
s developed. Eighty-nine patients, with a wide range of rhinoconjunctivitis
severity, scored a list of 91 problems for importance. The highest-scoring
problems were the practical problems: continually having to blow the nose,
rub the nose and eyes, and carry tissues. Patients were also bothered by s
leep impairments and systemic problems such as tiredness, poor concentratio
n and thirst. Questionnaires have also been developed for adolescents (12-1
7 years of age) - finding similar results to those for adults - and childre
n (6-12 years of age), who were troubled by their symptoms but did not have
the emotional dysfunction experienced by adults and adolescents. All three
questionnaires have strong measurement properties and have high reliabilit
y and good responsiveness, validity and interpretability. Quality-of-life q
uestionnaires can be used in clinical studies to help elucidate which treat
ments are preferred by patients and the efficacy of treatment regimens. Dis
ease-specific quality-of-life questionnaires can also be used during routin
e assessments and may reveal problems not spontaneously volunteered by pati
ents, particularly children. Results can also be compared at each clinic vi
sit to determine whether each intervention has been beneficial.