Prognostic factors for otitis media with effusion in infants

To determine the prognostic factors for otitis media with effusion (OME) in 1-year-old infants, we studied 240 patients and 366 controls in a case-coh ort study. On univariate analysis factors which were associated with OME we re family history, older siblings, upper respiratory infections and acute o titis media (AOM). After multivariate analysis, however, only the occurrenc e of more than four upper respiratory infections and children with older si blings were associated with OME. Thus, upper respiratory infections and old er siblings appear to be related to the development of OME.