Cellular, synaptic, network, and modulatory mechanisms involved in rhythm generation

The membrane properties and the synaptic interactions of individual neurons , as well as the interactions between neuronal networks, all contribute to the formation of the complex patterns of activity that underlie rhythmic mo tor patterns and slow-wave sleep rhythms. These properties and interactions are potential points of modulation for further refining network output. Re cent work illustrates the range of these properties and interactions and su ggests how they may be modulated.