Background. Several diverse strategies have been recommended to manage Jeho
vah's Witness patients undergoing surgery when significant blood loss is ex
pected. However, many of the proposed management strategies cannot be used
when the urgent nature of the disease precludes adequate preoperative prepa
ration of the patient. We present our experience of the management of two J
ehovah's Witnesses with oral carcinoma requiring extensive resection, neck
dissection, and reconstruction with free tissue transfer.
Methods. Hypervolemic hemodilution, hypotensive anesthesia, meticulous surg
ical hemostasis, and antifibrinolytic therapy were used as an alternative t
o blood products or transfusion.
Results. Radical surgical ablation and state-of-the-art reconstruction were
possible, as a single-stage procedure, even though blood transfusion or bl
ood product replacement therapy was refused.
Conclusion. Radical surgical ablation of oral carcinoma, with free tissue t
ransfer reconstruction, is possible in this group of patients without the u
se of blood products or transfusion. There would have been no advantage in
raising the red cell mass preoperatively, as the packed cell volume was ide
al for free tissue transfer. (C) 1999 John Wiley & Sons, Inc.